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trypsin-like serine protease
Increased in areas of Alzheimer's brain where 1/2 life of somatostatin is decreased.
Interactions
molecular events
General
serine protease trypsin family
Properties
STATE: active state
MOTIF: charge relay system
MOTIF: aspartate residue
histidine residue
serine residue
References
- Weber SJ, Louis RB, Trombley L, Bissette G, Davies P, Davis TP.
Metabolic half-life of somatostatin and peptidase activities
are altered in Alzheimer's disease.
J Gerontol. 1992 Jan;47(1):B18-25.
PMID: 1346149