enzymatic reaction

A chemical reaction catalyzed by an enzyme. An enzymatic reaction consists of substrate(s), enzyme & product(s). The enzyme is unchanged by the reaction.

Properties

GENERAL: catalytic reaction SPECIFIC: biochemical ligation sialylation active transport protein phosphorylation proteolytic cleavage template-directed reaction ENZYME: protease COMPARTMENT: lysosome STATE: active state MOTIF: active site SUBSTRATE: amyloid precursor protein COMPARTMENT: lysosome MOTIF: cysteine-rich region sulfotyrosine site MODIFICATION: sulfate Zn+2-binding site acidic region MOTIF: acidic residue (SEVERAL) binding site FOR-BINDING-OF: heparan sulfate binding site FOR-BINDING-OF: collagenase-4 MOTIF: O-glycosylation site N-glycosylation site (2) domain MOTIF: proteolytic site transmembrane domain {627-648} Thr phosphorylation site {T654} Ser phosphorylation site {S655} binding site FOR-BINDING-OF: Go protein NPXY motif NAME: NPXY motif FOR-BINDING-OF: amyloid beta A4 protein-binding family B member 1 MOTIF-SEQUENCE: Asn-Pro-Thr-Tyr S/T-phosphate {C-TERMINAL} PRECURSOR-FOR: A4 amyloid peptide COMPARTMENT: extracellular compartment INHIBITS: collagenase-4 PRODUCT: peptide COMPARTMENT: lysosome

References

Marx Science 'Research News' 249:984 1990