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clipsin (chymotrypsin-like protease, CTRL, CTRL-1)
Function:
- protease with specificity similar to chymotrypsin
Structure:
- extensively glycosylated
- belongs to the peptidase S1 family
- contains 1 peptidase S1 domain
Notes:
- inhibited by DFP, tosyl-phenylalanyl-chloromethane, chymostatin, soybean trypsin inhibitor, alpha-1-anti-chymotrypsin, alpha-2-macroglobulin
Interactions
molecular events
General
serine protease
Properties
SIZE: entity length = 26 aa
MW = 3 kD
COMPARTMENT: tissue
WITHIN: brain
ORGANISM: Rattus (rat)
STATE: active state
MOTIF: S1 domain {1}
Database Correlations
OMIM 118888
UniProt P40313
References
- Nelson RB, Siman R.
Clipsin, a chymotrypsin-like protease in rat brain which is
irreversibly inhibited by alpha-1-antichymotrypsin.
J Biol Chem. 1990 Mar 5;265(7):3836-43.
PMID: 2303481
- UniProt :accession P34168
Component-of
molecular complex