Search
regulatory factor X-associated protein; RFX-associated protein; RFX DNA-binding complex 36 kD subunit (RFXAP)
Function:
- part of the RFX complex that binds to the X-box of MHC II promoters
- phosphorylated
Compartment: nucleus
Expression: ubiquitous
Pathology:
- defects in RFXAP are a cause of bare lymphocyte syndrome type-2
General
nuclear protein
protein subunit
Properties
SIZE: entity length = 272 aa
MW = 28 kD
MOTIF: alanine-rich region {38-41}
MOTIF: alanine residue (SEVERAL)
nuclear translocation signal {163-178}
MOTIF: lysine-rich region {171-178}
MOTIF: lysine residue (SEVERAL)
Database Correlations
OMIM correlations
UniProt O00287
Entrez Gene 5994
Kegg hsa:5994
References
- UniProt :accession O00287
- RFXAPbase; Note: RFXAP mutation db
http://bioinf.uta.fi/RFXAPbase/
Component-of
regulatory factor X (RFX)