GA-binding protein transcription factor beta 1; GABP subunit beta-1; GABPB-1; GABP subunit beta-2; GABPB-2; transcription factor E4TF1-53; transcription factor E4TF1-47; nuclear respiratory factor 2 (GABPB1, E4TF1B, GABPB, GABPB2)

Function: - beta subunit of GA-binding protein - interacts with HCFC1, causing repression of transcriptional activity Structure: - related to Drosophila Notch protein - contains 5 ANK repeats Compartment: nucleus Alternative splicing: named isoforms=4

General

Ets family protein protein subunit

Properties

SIZE: entity length = 395 aa MW = 42 kD MOTIF: ankyrin repeat NAME: ankyrin repeat SITE: 5-34 ankyrin repeat NAME: ankyrin repeat SITE: 37-66 ankyrin repeat NAME: ankyrin repeat SITE: 70-99 ankyrin repeat NAME: ankyrin repeat SITE: 103-132 ankyrin repeat NAME: ankyrin repeat SITE: 136-166 transcriptional activation domain SITE: 258-327

Database Correlations

OMIM 600610 UniProt Q06547 Pfam PF00023 Kegg hsa:2553

References

- Macleod K, Leprince D, Stehelin D. The ets gene family. Trends Biochem Sci. 1992 Jul;17(7):251-6. Review. PMID: 1502727