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histone-H3
Function:
1) core component of nucleosome
2) H3 Lys-9 methylation is a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones
3) methylated on Lys-9 by SETDB2
4) H3 tails trimethylated on Lys-4 (H3K4Me3)
a) mark transcription start sites of virtually all active genes
b) recognized by BPTF (FALZ), component of the NuRF complex
General
histone
Properties
QUANTITY: 2
Database Correlations
OMIM 142780
References
- UniProt :accession Q96T68
- UniProt :accession Q12830
Component-of
nucleosome