polycomb protein SCMH1 (sex comb on midleg homolog 1, SCMH1)

Function: - component of the Polycomb group multiprotein PRC1 complex - interacts with the SAM domain of PHC1 via its SAM domain in vitro Structure: - belongs to the SCM family - contains 2 MBT repeats - contains 1 SAM domain (sterile alpha motif) Compartment: nucleus Alternative splicing: named isoforms=5 Expression: - strongly expressed in heart, muscle & pancreas - weakly expressed in brain, placenta, lung, liver & kidney

General

phosphoprotein protein subunit

Properties

SIZE: MW = 73 kD entity length = 660 aa COMPARTMENT: cell nucleus MOTIF: MBT {28-126} MBT {134-235} sterile alpha motif NAME: sterile alpha motif SITE: 593-658 MOTIF: Ser phosphorylation site {S649}

Database Correlations

UniProt Q96GD3 PFAM correlations

References

UniProt :accession Q96GD3