pleiotropic regulator 1 (PLRG1)

Function: - necessary for spliceosome assembly & for pre-mRNA splicing - binds CDC5L - component of CDC5L multiprotein complex Compartment: present in nuclear speckles

General

splicing factor; snRNP-associated protein WD repeat protein family

Properties

SIZE: MW = 57 kD entity length = 514 aa COMPARTMENT: cell nucleus MOTIF: WD repeat {202-241} WD repeat {244-283} WD repeat {286-325} WD repeat {328-367} WD repeat {370-410} WD repeat {411-449} WD repeat {460-499}

Database Correlations

OMIM 605961 UniProt O43660 Pfam PF00400

References

Uniprot :accession O43660