ATP-dependent RNA helicase DHX35; DEAH box protein 35 (DHX35, C20orf15, DDX35)

Function: - may be involved in pre-mRNA splicing - identified in the spliceosome C complex ATP + H₂O = ADP + phosphate Structure: - belongs to the DEAD box helicase family, DEAH subfamily - contains 1 helicase ATP-binding domain - contains 1 helicase C-terminal domain

Properties

SIZE: entity length = 703 aa MW = 79 kD COMPARTMENT: cell nucleus MOTIF: helicase NAME: helicase SITE: 64-229 MOTIF: ATP-binding site NAME: ATP-binding site SITE: 77-84 DEAD/H box NAME: DEAD/H box SITE: 176-179 Helicase C-terminal {261-438} DNA-binding motif active site MOTIF: P-loop FOR-BINDING-OF: adenosine triphosphate

Database Correlations

UniProt Q9H5Z1 PFAM correlations Entrez Gene 60625 Kegg hsa:60625 ENZYME 3.6.4.13

References

UniProt :accession Q9H5Z1