oncostatin-M specific receptor subunit beta (OSMR, OSMRB)

Function: - component of oncostatin-M specific receptor Compartment: membrane Alternative splicing: named isoforms=3 Expression: - expressed in all neural cells, fibroblasts, epithelial cells Pathology: - expressed in tumor cell lines

General

glycoprotein membrane protein protein subunit

Properties

SIZE: MW = 111 kD entity length = 979 aa MOTIF: signal sequence {1-27} N-glycosylation site {N163} cysteine residue {C245} MODIFICATION: cysteine residue {C255} cysteine residue {C255} MODIFICATION: cysteine residue {C245} N-glycosylation site {N326} fibronectin type III domain or F3 module {332-424} MOTIF: N-glycosylation site {N380} WSXWS motif {415-419} fibronectin type III domain or F3 module {430-524} MOTIF: N-glycosylation site {N446} fibronectin type III domain or F3 module {526-619} MOTIF: N-glycosylation site {N580} fibronectin type III domain or F3 module {625-732} transmembrane domain {741-761} box1 motif SITE: 770-778 FOR-BINDING-OF: Janus kinase (JAK)

Database Correlations

OMIM 601743 MORBIDMAP 601743 UniProt Q99650 Pfam PF00041 Kegg hsa:9180

References

UniProt :accession Q99650