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1) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} SV40 T antigen PRODUCT: molecular complex (retinoblastoma-associated protein -[SV40 T] SV40 T antigen -[RB1]) 2) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} adenovirus E1a PRODUCT: molecular complex (retinoblastoma-associated protein -[E1a] adenovirus E1a -[RB1]) 3) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} papillomavirus E7 PRODUCT: molecular complex (retinoblastoma-associated protein -[E7] papillomavirus E7 -[RB1]) 4) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} E2F {CELL_NUCLEUS} PRODUCT: molecular complex (retinoblastoma-associated protein -[E2F] E2F -[RB1]) 5) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} E3 ubiquitin-protein ligase Mdm2 {CYTOPLASM} {CELL_NUCLEUS} -[Zn+2] PRODUCT: molecular complex (retinoblastoma-associated protein -[MDM2] E3 ubiquitin-protein ligase Mdm2 -[Zn+2 RB1]) 6) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} death domain protein p84 {CELL_NUCLEUS} PRODUCT: molecular complex (retinoblastoma-associated protein -[p84] death domain protein p84 -[RB1]) 7) ==> binding SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} histone-binding protein RBBP7 {CELL_NUCLEUS} PRODUCT: molecular complex (retinoblastoma-associated protein histone-binding protein RBBP7 {CELL_NUCLEUS}) 8) ==> binding SUBSTRATE: histone deacetylase 1 {CELL_NUCLEUS} retinoblastoma-associated protein {CELL_NUCLEUS} E2F {CELL_NUCLEUS} transcription factor DP-1 {CELL_NUCLEUS} PRODUCT: molecular complex (histone deacetylase 1 -[RB1] retinoblastoma-associated protein E2F -[RB1] transcription factor DP-1) 9) ==> protein phosphorylation ENZYME: CDK1/cyclin-A complex {CELL_NUCLEUS} (cyclin-dependent kinase-1-PHOSPHATE -[cyclin A {CELL_NUCLEUS}] cyclin A -[CDK1]) SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} adenosine triphosphate PRODUCT: retinoblastoma-associated protein-PHOSPHATE {CELL_NUCLEUS} adenosine 5'-diphosphate 10) ==> protein phosphorylation ENZYME: CDK2/cyclin E complex (cyclin-dependent kinase-2-PHOSPHATE -[cyclin E] cyclin E-PHOSPHATE -[CDK2]) SUBSTRATE: retinoblastoma-associated protein {CELL_NUCLEUS} adenosine triphosphate PRODUCT: retinoblastoma-associated protein-PHOSPHATE {CELL_NUCLEUS} adenosine 5'-diphosphate