retrieval

1) ==> enzymatic reaction ENZYME: A disintegrin & metalloproteinase domain 17 {PLASMA_MEMBRANE} SUBSTRATE: Notch1 intracellular domain notch-1 (Drosophila) homolog protein {PLASMA_MEMBRANE} PRODUCT: Notch1 intracellular domain notch-1 (Drosophila) homolog protein {PLASMA_MEMBRANE} 2) ==> enzymatic reaction ENZYME: APP gamma-secretase (nicastrin presenilin-1 pen-2 protein Aph-1 protein) SUBSTRATE: Notch extracellular truncation PRODUCT: Notch1 intracellular domain peptide 3) ==> enzymatic reaction ENZYME: furin {PLASMA_MEMBRANE} {GOLGI} SUBSTRATE: notch-1 (Drosophila) homolog protein {PLASMA_MEMBRANE} PRODUCT: Notch1 intracellular domain notch-1 (Drosophila) homolog protein {PLASMA_MEMBRANE}