retrieval

1) ==> enzymatic reaction ENZYME: multienzyme complex {SMOOTH_ENDOPLASMIC_RETICULUM} (heme oxygenase-1 cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: heme {SMOOTH_ENDOPLASMIC_RETICULUM.367268} O2 NADPH PRODUCT: biliverdin {SMOOTH_ENDOPLASMIC_RETICULUM.367272} carbon monoxide NADP :CELL MACROPHAGE 2) ==> enzymatic reaction ENZYME: multienzyme complex (cholesterol 20,22 desmolase adrenodoxin, mitochondrial adrenodoxin reductase -[FAD NADP NADP NADP]) SUBSTRATE: cholesterol NADPH O2 PRODUCT: pregnenolone isocaproate {MEMBRANE.1676} NADP 3) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-17-alpha hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: pregnenolone O2 NADPH PRODUCT: 17-OH pregnenolone NADP 4) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-17-alpha hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: 17-OH pregnenolone O2 NADPH PRODUCT: dehydroepiandrosterone NADP 5) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-17-alpha hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: progesterone O2 NADPH PRODUCT: 17-hydroxyprogesterone NADP 6) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-17-alpha hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: 17-hydroxyprogesterone O2 NADPH PRODUCT: androstenedione NADP 7) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-21-hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: progesterone O2 NADPH PRODUCT: 11-deoxycorticosterone NADP 8) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-21-hydroxylase cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: 17-hydroxyprogesterone O2 NADPH PRODUCT: 11-deoxycortisol NADP 9) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-11-beta hydroxylase adrenodoxin, mitochondrial adrenodoxin reductase -[FAD NADP NADP NADP]) SUBSTRATE: 11-deoxycorticosterone NADPH O2 PRODUCT: corticosterone NADP 10) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-11-beta hydroxylase adrenodoxin, mitochondrial adrenodoxin reductase -[FAD NADP NADP NADP]) SUBSTRATE: 11-deoxycortisol NADPH O2 PRODUCT: cortisol NADP 11) ==> enzymatic reaction ENZYME: multienzyme complex (steroid-11-beta hydroxylase adrenodoxin, mitochondrial adrenodoxin reductase -[FAD NADP NADP NADP]) SUBSTRATE: corticosterone NADPH O2 PRODUCT: aldosterone NADP 12) ==> enzymatic reaction ENZYME: multienzyme complex {SMOOTH_ENDOPLASMIC_RETICULUM} (heme oxygenase-2 cytochrome P450 reductase -[NADP NADP]) SUBSTRATE: heme O2 NADPH PRODUCT: biliverdin carbon monoxide NADP