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1) ==> binding SUBSTRATE: Mdm4 protein {CELL_NUCLEUS} -[Zn+2] cellular tumor antigen p53 {cytoplasm} {cell nucleus} {endoplasmic reticulum} PRODUCT: molecular complex (Mdm4 protein -[Zn+2] cellular tumor antigen p53 ) 2) ==> binding SUBSTRATE: Mdm4 protein {CELL_NUCLEUS} -[Zn+2] tumor protein p73 {cell nucleus} PRODUCT: molecular complex (Mdm4 protein -[Zn+2] tumor protein p73) 3) ==> binding SUBSTRATE: Mdm4 protein {CELL_NUCLEUS} -[Zn+2] E3 ubiquitin-protein ligase Mdm2 {CYTOPLASM} {CELL_NUCLEUS} -[Zn+2] PRODUCT: molecular complex (Mdm4 protein -[Zn+2] E3 ubiquitin-protein ligase Mdm2 -[Zn+2])