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retrieval
1) ==> binding
SUBSTRATE:
immunoglobulin {PLASMA}
leukosialin {PLASMA_MEMBRANE}
PRODUCT:
leukosialin {PLASMA_MEMBRANE}
-[Ig]
:CELL MONONUCLEAR_LEUKOCYTE
2) ==> binding
SUBSTRATE:
T-cell receptor/CD3 complex {PLASMA_MEMBRANE}
(T cell receptor
(T cell receptor alpha
T cell receptor beta
T cell receptor signalling subunit)
CD3
(T-cell surface glycoprotein CD3 gamma chain
T-cell surface glycoprotein CD3 epsilon chain
T-cell surface glycoprotein CD3 zeta chain ))
immunoglobulin {PLASMA}
PRODUCT:
molecular complex
(T-cell receptor/CD3 complex
(T cell receptor
(T cell receptor alpha
T cell receptor beta
T cell receptor signalling subunit)
CD3
(T-cell surface glycoprotein CD3 gamma chain
T-cell surface glycoprotein CD3 epsilon chain
T-cell surface glycoprotein CD3 zeta chain ))
immunoglobulin)
3) ==> binding
SUBSTRATE:
CD2 {PLASMA_MEMBRANE}
immunoglobulin {PLASMA}
PRODUCT:
CD2 {PLASMA_MEMBRANE}
-[Ig]
:CELL T_LYMPHOCYTE
4) ==> mediation
CAUSE:
binding
SUBSTRATE: T-cell receptor/CD3 complex {PLASMA_MEMBRANE}
(T cell receptor
(T cell receptor alpha
T cell receptor beta
T cell receptor signalling subunit)
CD3
(T-cell surface glycoprotein CD3 gamma chain
T-cell surface glycoprotein CD3 epsilon chain
T-cell surface glycoprotein CD3 zeta chain ))
immunoglobulin {PLASMA}
PRODUCT: molecular complex
(T-cell receptor/CD3 complex
(T cell receptor
(T cell receptor alpha
T cell receptor beta
T cell receptor signalling subunit)
CD3
(T-cell surface glycoprotein CD3 gamma chain
T-cell surface glycoprotein CD3 epsilon chain
T-cell surface glycoprotein CD3 zeta chain ))
immunoglobulin)
EFFECT:
protein phosphorylation
ENZYME: protein kinase
SUBSTRATE: ets2 proto-oncogene protein
adenosine triphosphate
PRODUCT: ets2 proto-oncogene protein-PHOSPHATE
adenosine 5'-diphosphate
:CELL JURKAT_CELL
5) ==> mediation
CAUSE:
binding
SUBSTRATE: CD2 {PLASMA_MEMBRANE}
immunoglobulin {PLASMA}
PRODUCT: CD2 {PLASMA_MEMBRANE}
-[Ig]
:CELL T_LYMPHOCYTE
EFFECT:
binding
SUBSTRATE: Go-alpha {PLASMA_MEMBRANE}
-[GTP]
phospholipase C {CYTOPLASM}
-[G-alpha]
PRODUCT: phospholipase C {CYTOPLASM}
-[G-alpha]