retrieval

1) ==> chemical reaction SUBSTRATE: cholesterol ozone PRODUCT: cholesterol metabolite 1 H2O 2) ==> chemical reaction SUBSTRATE: cholesterol ozone PRODUCT: cholesterol metabolite 2 H2O 3) ==> enzymatic reaction ENZYME: pyruvate carboxylase {MITOCHONDRIA} SUBSTRATE: pyruvate CO2 adenosine triphosphate H2O PRODUCT: oxaloacetate adenosine 5'-diphosphate H2PO4- 4) ==> enzymatic reaction ENZYME: fructose-1,6-diphosphatase {CYTOPLASM} -[citrate] SUBSTRATE: fructose-1,6-diphosphate H2O PRODUCT: fructose-6-phosphate H2PO4- 5) ==> enzymatic reaction ENZYME: glucose-6-phosphatase {ENDOPLASMIC_RETICULUM} SUBSTRATE: glucose-6-phosphate (Robison ester) H2O PRODUCT: glucose H2PO4- 6) ==> enzymatic reaction ENZYME: fumarase {MITOCHONDRIA} {CYTOPLASM} SUBSTRATE: fumarate {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: malate {MITOCHONDRIAL_MATRIX.2612} 7) ==> enzymatic reaction ENZYME: lactonase SUBSTRATE: 6-phospho gluconolactone H2O PRODUCT: 6-phosphogluconate 8) ==> enzymatic reaction ENZYME: arginase-1 {CYTOPLASM} SUBSTRATE: arginine H2O PRODUCT: ornithine urea {PLASMA.1202} {SERUM.1203} 9) ==> enzymatic reaction ENZYME: cytochrome c oxidase {INNER_MITOCHONDRIAL_MEMBRANE} (cytochrome a cytochrome a3 cytochrome c oxidase subunit 1 cytochrome c oxidase subunit 2 cytochrome c oxidase subunit 3 cytochrome c oxidase subunit 4 isoform 1, mitochondrial cytochrome c oxidase subunit 5 cytochrome c oxidase subunit 6 cytochrome c oxidase subunit 7 cytochrome c oxidase subunit 8A, mitochondrial {MITOCHONDRIA} cytochrome c oxidase subunit 9 cytochrome c oxidase subunit 10) SUBSTRATE: H+ O2 {MITOCHONDRIA.1183} cytochrome c -[[]] PRODUCT: H+ H2O {MITOCHONDRIA.1183} cytochrome c -[[]] 10) ==> enzymatic reaction ENZYME: HMG CoA synthase {CYTOPLASM} SUBSTRATE: acetyl-CoA {CYTOPLASM.1134} acetoacetyl-CoA {CYTOPLASM.1134} H2O PRODUCT: hydroxymethylglutaryl CoA {CYTOPLASM.1134} coenzyme A {CYTOPLASM.1134} 11) ==> enzymatic reaction ENZYME: squalene epoxidase {SMOOTH_ENDOPLASMIC_RETICULUM} -[NADPH] SUBSTRATE: squalene NADPH O2 PRODUCT: squalene epoxide NAD H2O 12) ==> enzymatic reaction ENZYME: squalene oxidocyclase {SMOOTH_ENDOPLASMIC_RETICULUM} (squalene epoxidase -[NADPH] lanosterol cyclase -[NADPH]) SUBSTRATE: squalene NADPH O2 PRODUCT: lanosterol NAD H2O 13) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: dopamine O2 H2O PRODUCT: 3,4-dihydroxy-phenylacetate hydrogen peroxide NH3 14) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: 3-methoxydopamine O2 H2O PRODUCT: homovanillate hydrogen peroxide NH3 15) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: norepinephrine O2 H2O PRODUCT: 3,4-dihydroxymandellic acid hydrogen peroxide NH3 16) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: normetanephrine O2 H2O PRODUCT: vanillylmandelate methoxyhydroxyphenylglycol hydrogen peroxide NH3 17) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: epinephrine O2 H2O PRODUCT: 3,4-dihydroxymandellic acid hydrogen peroxide NH3 18) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: metanephrine O2 H2O PRODUCT: vanillylmandelate methoxyhydroxyphenylglycol hydrogen peroxide NH3 19) ==> enzymatic reaction ENZYME: 5-oxoprolinase SUBSTRATE: 5 oxoproline adenosine triphosphate H2O PRODUCT: glutamate adenosine 5'-diphosphate H2PO4- 20) ==> enzymatic reaction ENZYME: dipeptidase SUBSTRATE: cysteinylglycine {CYTOPLASM.1134} H2O PRODUCT: cysteine glycine 21) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: tryptamine NADH H2O O2 PRODUCT: tryptophal NAD NH3 hydrogen peroxide 22) ==> enzymatic reaction ENZYME: tryptophan hydroxylase -[BH4] SUBSTRATE: tryptophan O2 NADPH PRODUCT: 5-hydroxytryptophan H2O NADP 23) ==> enzymatic reaction ENZYME: monoamine oxidase SUBSTRATE: serotonin NADH H2O O2 PRODUCT: 5-OH tryptophal NAD NH3 hydrogen peroxide 24) ==> enzymatic reaction ENZYME: formamidase SUBSTRATE: N-formyl kynurenine H2O PRODUCT: kynurenine formate 25) ==> enzymatic reaction ENZYME: kynureninase {CYTOPLASM} -[ACETYL] SUBSTRATE: kynurenine H2O PRODUCT: anthranilate alanine 26) ==> enzymatic reaction ENZYME: kynurenine 3-monooxygenase {MITOCHONDRIA} SUBSTRATE: kynurenine O2 NADPH PRODUCT: 3-hydroxykynurenine H2O NADP 27) ==> enzymatic reaction ENZYME: hydroxylase SUBSTRATE: anthranilate O2 NADPH PRODUCT: 3-hydroxyanthranilate H2O NADP 28) ==> enzymatic reaction ENZYME: kynureninase {CYTOPLASM} -[ACETYL] SUBSTRATE: 3-hydroxykynurenine H2O PRODUCT: 3-hydroxyanthranilate alanine 29) ==> enzymatic reaction ENZYME: protease SUBSTRATE: protein H2O PRODUCT: peptide trimethyllysine 30) ==> enzymatic reaction ENZYME: aldehyde dehydrogenase SUBSTRATE: gamma-trimethyl amino butyraldehyde NAD H2O PRODUCT: gamma-butyrobetaine NADH 31) ==> enzymatic reaction ENZYME: S-adenosyl homocysteine hydrolase {CYTOPLASM} SUBSTRATE: S-adenosylhomocysteine PRODUCT: homocysteine adenosine H2O 32) ==> enzymatic reaction ENZYME: cystathionine beta-synthase {CYTOPLASM} {CELL_NUCLEUS} -[B6-P] SUBSTRATE: homocysteine serine PRODUCT: cystathionine H2O 33) ==> enzymatic reaction ENZYME: hydrolase SUBSTRATE: N5,N10-methenyltetrahydrofolate adenosine 5'-diphosphate H2O PRODUCT: N10-formyltetrahydrofolate adenosine triphosphate 34) ==> enzymatic reaction ENZYME: arginase-1 {CYTOPLASM} SUBSTRATE: arginine {CYTOPLASM.1134} H2O PRODUCT: ornithine {CYTOPLASM.1134} urea {PLASMA.1202} {SERUM.1203} 35) ==> enzymatic reaction ENZYME: ATP citrate lyase {cytoplasm} SUBSTRATE: citrate {CYTOPLASM.1134} coenzyme A {CYTOPLASM.1134} adenosine triphosphate {CYTOPLASM.1134} H2O PRODUCT: oxaloacetate {CYTOPLASM.1134} acetyl-CoA {CYTOPLASM.1134} adenosine 5'-diphosphate {CYTOPLASM.1134} H2PO4- {CYTOPLASM.1134} 36) ==> enzymatic reaction ENZYME: carbamoyl phosphate synthase-1 {MITOCHONDRIAL_MATRIX} SUBSTRATE: CO2 NH3 H2O adenosine triphosphate {MITOCHONDRIAL_MATRIX.2612} PRODUCT: carbamoyl phosphate {MITOCHONDRIAL_MATRIX.2612} adenosine 5'-diphosphate {MITOCHONDRIAL_MATRIX.2612} H2PO4- {MITOCHONDRIAL_MATRIX.2612} 37) ==> enzymatic reaction ENZYME: dehydrogenase SUBSTRATE: UDP glucose NAD H2O PRODUCT: UDP glucuronate NADH 38) ==> enzymatic reaction ENZYME: glutamate dehydrogenase {mitochondria} SUBSTRATE: glutamate NADP H2O PRODUCT: alpha-ketoglutarate NADPH NH3 39) ==> enzymatic reaction ENZYME: hydrolase {INTESTINAL_LUMEN} SUBSTRATE: bilirubin diglucuronide {INTESTINAL_LUMEN.1217} H2O PRODUCT: bilirubin {INTESTINAL_LUMEN.1217} glucuronate {INTESTINAL_LUMEN.1217} :CELL NULL 40) ==> enzymatic reaction ENZYME: HMG CoA synthase {MITOCHONDRIAL_MATRIX} SUBSTRATE: acetyl-CoA {MITOCHONDRIAL_MATRIX.2612} acetoacetyl-CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: hydroxymethylglutaryl CoA {MITOCHONDRIAL_MATRIX.2612} 41) ==> enzymatic reaction ENZYME: inositol pentaphosphate-1-phosphatase SUBSTRATE: inositol-1,3,4,5,6-pentaphosphate {CYTOPLASM.1134} H2O adenosine triphosphate PRODUCT: inositol-3,4,5,6-tetraphosphate {CYTOPLASM.1134} adenosine 5'-diphosphate H2PO4- 42) ==> enzymatic reaction ENZYME: inositol pentaphosphate-3-phosphatase SUBSTRATE: inositol-1,3,4,5,6-pentaphosphate {CYTOPLASM.1134} H2O PRODUCT: inositol-1,4,5,6-tetraphosphate {CYTOPLASM.1134} H2PO4- 43) ==> enzymatic reaction ENZYME: inositol-1,3,4,5-tetraphosphate-5-phosphatase SUBSTRATE: inositol-1,3,4,5-tetraphosphate {CYTOPLASM.1134} H2O PRODUCT: inositol 1,3,4-triphosphate {CYTOPLASM.1134} H2PO4- 44) ==> enzymatic reaction ENZYME: phospholipase {LYSOSOME} SUBSTRATE: N-retinylidine-N-retinyl phosphatidyl ethanolamine {PLASMA_MEMBRANE.6309} H2O PRODUCT: N-retinylidine-N-retinyl ethanolamine {LYSOSOME.6305} phosphatidate {CELLULAR_MEMBRANE.1678} :CELL EPITHELIAL_CELL 45) ==> enzymatic reaction ENZYME: phosphomonoesterase SUBSTRATE: inositol 1,3,4-triphosphate {CYTOPLASM.1134} H2O PRODUCT: inositol H2PO4- 46) ==> enzymatic reaction ENZYME: xanthine oxidase {peroxisome} {cytoplasm} SUBSTRATE: hypoxanthine O2 H2O PRODUCT: xanthine hydrogen peroxide 47) ==> enzymatic reaction ENZYME: xanthine oxidase {peroxisome} {cytoplasm} SUBSTRATE: xanthine O2 H2O PRODUCT: urate {PLASMA.1202} {SERUM.1203} hydrogen peroxide 48) ==> enzymatic reaction ENZYME: inositol-trisphosphate 3-kinase C {CYTOPLASM} {CELL_NUCLEUS} SUBSTRATE: sarcosine O2 H2O PRODUCT: glycine formaldehyde hydrogen peroxide 49) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 50) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 51) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 52) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 53) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 54) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 55) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 56) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 57) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 58) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 59) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 60) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 61) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 62) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 63) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 64) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 65) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 66) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 67) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 68) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 69) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 70) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 71) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 72) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 73) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 74) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 75) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 76) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 77) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 78) ==> enzymatic reaction ENZYME: enol CoA hydratase {MITOCHONDRIAL_MATRIX} SUBSTRATE: trans-2-enoyl CoA {MITOCHONDRIAL_MATRIX.2612} H2O PRODUCT: 3-hydroxyacyl CoA {MITOCHONDRIAL_MATRIX.2612} 79) ==> uncatalyzed reaction SUBSTRATE: trans retinal phosphatidylethanolamine {CELLULAR_MEMBRANE.1678} PRODUCT: N-retinylidine-N-retinyl phosphatidyl ethanolamine {PLASMA_MEMBRANE.6309} H2O :CELL ROD