retrieval

1) ==> binding SUBSTRATE: bilirubin {PLASMA.1202} albumin {PLASMA} {SERUM} {CEREBROSPINAL_FLUID} PRODUCT: albumin {PLASMA} {SERUM} {CEREBROSPINAL_FLUID} -[bilirubin] :CELL NULL 2) ==> enzymatic reaction ENZYME: biliverdin reductase {SMOOTH_ENDOPLASMIC_RETICULUM} -[NADPH NADH] SUBSTRATE: biliverdin {SMOOTH_ENDOPLASMIC_RETICULUM.367278} NADPH PRODUCT: bilirubin {SMOOTH_ENDOPLASMIC_RETICULUM.367282} NADP :CELL MACROPHAGE 3) ==> enzymatic reaction ENZYME: UDP-glucuronosyltransferase-1A {CELLULAR_MEMBRANE} SUBSTRATE: bilirubin {SMOOTH_ENDOPLASMIC_RETICULUM.367305} UDP glucuronate PRODUCT: bilirubin diglucuronide {CELLULAR_COMPARTMENT.367309} uridine diphosphate :CELL HEPATOCYTE 4) ==> enzymatic reaction ENZYME: hydrolase {INTESTINAL_LUMEN} SUBSTRATE: bilirubin diglucuronide {INTESTINAL_LUMEN.1217} H2O PRODUCT: bilirubin {INTESTINAL_LUMEN.1217} glucuronate {INTESTINAL_LUMEN.1217} :CELL NULL 5) ==> enzymatic reaction ENZYME: oxidoreductase {INTESTINAL_LUMEN} SUBSTRATE: bilirubin {INTESTINAL_LUMEN.1217} PRODUCT: urobilinogen {INTESTINAL_LUMEN.1217} :CELL NULL