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Z-DNA-binding protein 1 (tumor stroma & activated macrophage protein DLM-1, ZBP1, C20orf183, DLM1)
Function:
- role in host defense against tumors & pathogens
- binds Z-DNA
Structure:
- contains 2 DRADA repeats
Alternative splicing: named isoforms=5
Expression:
- highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow & spleen
- expressed to a lesser extent in thymus, lung & liver
General
DNA-binding protein
Properties
SIZE: MW = 46 kD
entity length = 429 aa
COMPARTMENT: cell nucleus
MOTIF: DRADA {6-72}
DRADA {103-168}
Database Correlations
OMIM 606750
UniProt Q9H171
Pfam PF02295
References
UniProt :accession Q9H171