zinc finger Y chromosomal protein

Function: probable transcriptional activator Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family, ZFX/ZFY subfamily - contains 13 C2H2-type Zn⁺² fingers Compartment: nucleus Note: - originally thought to be the testis determining factor (TDF)

General

C2H2 type zinc finger protein DNA-binding protein transcription factor (TF)

Properties

SIZE: MW = 91 kD entity length = 801 aa COMPARTMENT: cell nucleus MOTIF: Zn finger C2H2-type SITE: 421-443 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 452-474 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 484-506 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 515-538 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 544-566 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 572-595 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 601-623 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 629-652 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 658-680 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 686-709 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 715-737 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 743-766 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 772-795 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 490000 UniProt P08048 PFAM correlations Kegg hsa:7544

References

UniProt :accession P08048