zinc finger X-chromosomal protein (ZFX)

Function: probable transcriptional activator Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family, ZFX/ZFY subfamily - contains 13 C2H2-type Zn⁺² fingers Compartment: nucleus Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein DNA-binding protein phosphoprotein transcription factor (TF)

Properties

SIZE: entity length = 805 aa MW = 91 kD COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S274} Zn finger C2H2-type SITE: 425-447 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 456-478 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 488-510 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 519-542 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 548-570 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 576-599 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 605-627 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 633-656 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 662-684 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 690-713 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 719-741 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 747-770 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 776-798 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 314980 UniProt P17010 PFAM correlations Kegg hsa:7543

References

UniProt :accession P17010