zinc finger protein 823; zinc finger protein ZFP-36 (ZNF823, ZFP36)

Function: may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 16 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable)

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 610 aa MW = 70 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-97 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 164-186 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 192-214 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 220-242 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 248-270 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 276-298 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 304-326 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 332-354 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 360-382 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 388-410 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 416-438 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 444-465 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 471-493 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 499-521 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 527-549 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 555-577 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 583-605 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 190700 UniProt P16415 PFAM correlations Kegg hsa:5555

References

UniProt :accession P16415