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zinc finger protein neuro-d4; BRG1-associated factor 45B; BAF45B; D4, Zn+2 & double PHD fingers family 1 (DPF1, BAF45B, NEUD4)
Function:
- role in developing neurons by participating in regulation of cell survival, possibly as a neuron-specific transcription factor (putative)
Structure:
- belongs to the requiem/DPF family
- contains 2 PHD-type Zn+2 fingers
Compartment: cytoplasm (putative), nucleus (potential)
Alternative splicing:
- named isoforms=3
- additional isoforms seem to exist
Notes:
- uncertain whether Met-1 or Met-28 is the initiator
General
nuclear protein
zinc finger protein
Properties
SIZE: entity length = 380 aa
MW = 43 kD
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: Zn finger PHD-type
NAME: Zn finger PHD-type
SITE: 254-311
EFFECTOR-BOUND: Zn+2
Zn finger PHD-type
NAME: Zn finger PHD-type
SITE: 308-368
EFFECTOR-BOUND: Zn+2
Database Correlations
OMIM 601670
UniProt Q92782
Pfam PF00628
Entrez Gene 8193
References
UniProt :accession Q92782
Component-of
nBAF complex (neuron-specific chromatin remodeling complex)