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zinc finger protein neuro-d4; BRG1-associated factor 45B; BAF45B; D4, Zn+2 & double PHD fingers family 1 (DPF1, BAF45B, NEUD4)

Function: - role in developing neurons by participating in regulation of cell survival, possibly as a neuron-specific transcription factor (putative) Structure: - belongs to the requiem/DPF family - contains 2 PHD-type Zn+2 fingers Compartment: cytoplasm (putative), nucleus (potential) Alternative splicing: - named isoforms=3 - additional isoforms seem to exist Notes: - uncertain whether Met-1 or Met-28 is the initiator

General

nuclear protein zinc finger protein

Properties

SIZE: entity length = 380 aa MW = 43 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: Zn finger PHD-type NAME: Zn finger PHD-type SITE: 254-311 EFFECTOR-BOUND: Zn+2 Zn finger PHD-type NAME: Zn finger PHD-type SITE: 308-368 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 601670 UniProt Q92782 Pfam PF00628 Entrez Gene 8193

References

UniProt :accession Q92782

Component-of

nBAF complex (neuron-specific chromatin remodeling complex)