zinc finger protein 93; zinc finger protein 505; zinc finger protein HTF34 (ZNF93, ZNF505)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 17 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=3 Expression: expressed early during embryonic development

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 620 aa MW = 71 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-75 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 145-167 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 173-195 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 201-223 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 229-251 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 257-279 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 285-307 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 313-335 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 341-363 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 369-391 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 397-419 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 425-447 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 453-475 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 481-503 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 509-531 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 537-559 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 565-587 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 593-615 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 603975 UniProt P35789 PFAM correlations Entrez Gene 7646 Kegg hsa:8193

References

UniProt :accession P35789