zinc finger protein 92; zinc finger protein HTF12 (ZNF92)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 16 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=3 Expression: expressed early during embryonic development

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 586 aa MW = 68 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-75 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 145-167 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 173-195 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 201-223 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 229-251 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 257-279 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 285-307 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 313-335 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 341-363 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 369-391 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 397-419 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 425-447 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 453-475 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 481-503 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 509-531 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 537-559 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 563-586 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 603974 UniProt Q03936 PFAM correlations Entrez Gene 168374 Kegg hsa:1683

References

UniProt :accession Q03936