zinc finger protein 74; hZNF7 (ZNF74, Cos52)

Function: may play a role in RNA metabolism Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 12 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus Alternative splicing: named isoforms=4 Expression: highly expressed in fetal brain

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: entity length = 643 aa MW = 72 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 43-114 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 247-269 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 275-297 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 303-325 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 331-353 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 359-381 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 387-409 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 415-437 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 443-465 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 471-493 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 499-521 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 527-549 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 555-577 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194548 UniProt Q16587 PFAM correlations

References

UniProt :accession Q16587