zinc finger protein 7; zinc finger protein KOX4; zinc finger protein HF.16 (ZNF7, KOX4)

Function: may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 15 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Expression: - ubiquitously present in many human cell lines of different embryological derivation

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 686 aa MW = 78 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-76 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 223-245 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 250-272 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 278-300 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 306-328 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 334-356 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 362-384 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 413-435 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 441-463 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 469-491 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 497-519 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 525-547 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 553-575 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 581-603 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 634-656 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 662-684 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194531 UniProt P17097 PFAM correlations Entrez Gene 7553 Kegg hsa:7553

References

UniProt :accession P17097