zinc finger protein 69; hZNF3; Cos5 (ZNF69)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 14 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 566 aa MW = 66 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 24-106 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 164-186 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 192-214 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 220-242 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 248-270 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 276-298 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 304-326 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 332-354 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 360-382 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 388-410 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 416-438 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 444-472 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 478-500 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 506-528 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 534-556 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194543 UniProt Q9UC07 PFAM correlations Entrez Gene 7620 Kegg hsa:7620

References

UniProt :accession Q9UC07