zinc finger protein 675 (TRAF6-inhibitory Zn+2 finger protein, TRAF6-binding zinc finger protein, ZNF675, TIZ)

Function: - may be involved in transcriptional regulation - may play a role during osteoclast differentiation by modulating TRAF6 signaling activity - interacts with TRAF6 Structure: - contains 15 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus (probable)

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: entity length = 568 aa MW = 66 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-75 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 144-166 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 172-194 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 200-222 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 228-250 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 256-278 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 284-306 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 312-334 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 340-362 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 368-390 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 396-418 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 424-446 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 452-474 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 480-502 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 508-530 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 536-558 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q8TD23 PFAM correlations

References

UniProt :accession Q8TD23