zinc finger protein 641 (ZNF641)

Function: - transcriptional activator - activates transcriptional activities of SRE & AP-1 Structure: - belongs to the krueppel C2H2-type zinc-finger protein family - contains 5 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus Alternative splicing: named isoforms=2 Expression: - expressed in skeletal muscle > heart, liver, pancreas > placenta - not expressed in brain, lung, kidney

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: MW = 50 kD entity length = 438 aa COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 109-181 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Transactivation {171-265} Zn finger C2H2-type SITE: 264-286 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 292-314 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 320-342 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 372-394 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 400-422 EFFECTOR-BOUND: Zn+2

References

UniProt :accession Q96N77