zinc finger protein 57 homolog (Zfp-57, zinc finger protein 698, ZFP57, C6orf40, ZNF698)

Function: - acts as a transcriptional repressor in Schwann cells Structure: - belongs to the krueppel C2H2-type zinc-finger protein family - contains 7 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein transcriptional silencer (transcriptional repressor)

Properties

SIZE: MW = 52 kD entity length = 452 aa COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 16-88 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 91-113 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 119-141 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 147-169 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 175-197 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 300-322 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 328-350 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 356-378 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q9NU63 PFAM correlations

References

UniProt :accession Q9NU63