zinc finger protein 550 (ZNF550)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 8 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=2 Note: - uncertain whether Met-1 or Met-10 is the initiator

General

C2H2 type zinc finger protein DNA-binding protein phosphoprotein

Properties

SIZE: entity length = 422 aa MW = 48 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 12-83 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 203-225 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 231-253 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 259-281 EFFECTOR-BOUND: Zn+2 MOTIF: Tyr phosphorylation site {Y259} Zn finger C2H2-type SITE: 287-309 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 315-337 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 343-365 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 371-393 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 399-421 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q7Z398 Pfam PF01352 Entrez Gene 162972 Kegg hsa:162972

References

UniProt :accession Q7Z398