zinc finger protein 468 (ZNF468)

Function: role in transcriptional regulation (putative) Structure: - belongs to the krueppel C2H2-type zinc-finger protein family - contains 11 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus Alternative splicing: named isoforms=2 Expression: - isoform 1 & 2 are expressed in placenta, pancreas, small intestine > colon, ovary, testis, prostate, thymus, spleen, kidney, liver - no expression detected in heart, brain

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: MW = 61 kD entity length = 522 aa COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 8-80 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 215-237 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 243-265 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 271-293 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 299-321 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 327-349 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 355-377 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 383-405 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 411-433 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 439-461 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 467-489 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 495-517 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q5VIY5 PFAM correlations

References

UniProt :accession Q5VIY5