zinc finger protein 45; BRC1744; zinc finger protein 13; zinc finger protein KOX5 (ZNF45, KOX5, ZNF13)

Function: may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 18 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 682 aa MW = 78 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 8-78 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 164-186 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 192-214 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 220-247 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 248-275 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 276-298 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 304-326 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 332-354 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 360-382 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 388-410 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 416-438 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 444-466 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 472-494 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 500-522 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 528-550 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 556-578 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 584-606 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 612-634 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 640-662 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194554 UniProt Q02386 PFAM correlations LOCUS-LINK correlations Kegg hsa:7596

References

UniProt :accession Q02386