zinc finger protein 44; zinc finger protein KOX7; gonadotropin-inducible transcription repressor 2; GIOT-2; zinc finger protein 58 (ZNF44, KOX7, ZNF58)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 16 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable)

General

C2H2 type zinc finger protein phosphoprotein transcription factor (TF)

Properties

SIZE: entity length = 589 aa MW = 68 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-90 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 141-163 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 169-191 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 197-219 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 225-247 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 253-275 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 281-303 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 309-331 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 337-359 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 365-387 EFFECTOR-BOUND: Zn+2 MOTIF: Ser phosphorylation site {S379} Zn finger C2H2-type SITE: 393-415 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 421-443 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 449-470 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 476-498 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 504-526 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 532-554 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 560-582 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194542 UniProt P15621 PFAM correlations Entrez Gene 51710 Kegg hsa:5171

References

UniProt :accession P15621