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zinc finger protein 330; nucleolar autoantigen 36; nucleolar cysteine-rich protein (ZNF330 NOA36)
Structure: belongs to the NOA36 family
Compartment:
- nucleus, nucleolus chromosome, centromere
- predominantly in the nucleolus
- in mitosis, associated with centromeres
- concentrated at the midbody in cytokinesis
Expression:
- widely expressed
- higher expression seen in heart & skeletal muscle
General
nuclear protein
phosphoprotein
zinc finger protein
Properties
SIZE: entity length = 320 aa
MW = 36 kD
COMPARTMENT: cell nucleus
MOTIF: nuclear translocation signal {3-11}
Zn finger C4-type
SITE: 42-58
EFFECTOR-BOUND: Zn+2
Zn finger C4-type
SITE: 67-104
EFFECTOR-BOUND: Zn+2
Zn finger C4-type
SITE: 129-149
EFFECTOR-BOUND: Zn+2
Zn finger C4-type
SITE: 175-189
EFFECTOR-BOUND: Zn+2
acidic region {269-286}
MOTIF: acidic residue (SEVERAL)
Tyr phosphorylation site {Y308}
Tyr phosphorylation site {Y315}
Database Correlations
OMIM 609550
UniProt Q9Y3S2
Pfam PF06524
Entrez Gene 27309
Kegg hsa:27309
References
UniProt :accession Q9Y3S2