zinc finger protein 320 (ZNF320)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type zinc-finger protein family - contains 12 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus (probable) Expression: - expressed at high levels in placenta, pancreas, kidney & heart, & at lower levels in liver, skeletal muscle & brain Pathology: - chromosomal translocation t(10;19)(q26;q13.3) involving ZNF320 with BRWD2/WDR11 is found in a form of glioblastoma

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: entity length = 509 aa MW = 59 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 8-80 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 161-183 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 189-211 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 217-239 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 245-267 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 273-295 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 301-323 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 329-351 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 357-379 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 385-407 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 413-435 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 441-463 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 469-491 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 606427 UniProt A2RRD8 PFAM correlations Entrez Gene 117040

References

UniProt :accession A2RRD8