zinc finger protein 317 (ZNF317, KIAA1588)

Function: - may function as a transcription factor - role in erythroid maturation & lymphoid proliferation (putative) Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 13 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=4 Expression: - isoform 1 & isoform 2 are ubiquitously expressed - isoform 3 & isoform 4 are expressed only in lymphocytes, spleen & lung

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: entity length = 595 aa MW = 68 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 57-128 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 222-244 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 250-272 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 278-300 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 306-328 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 334-356 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 362-384 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 390-412 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 418-440 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 446-468 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 474-496 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 502-524 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 530-552 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 558-580 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 613864 UniProt Q96PQ6 Pfam PF01352 Entrez Gene 57693 Kegg hsa:57693