zinc finger protein 292 (ZNF292, KIAA0530)

Function: - may be involved in transcriptional regulation - phosphorylated upon DNA damage, probably by ATM or ATR Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 15 C2H2-type Zn⁺² fingers Compartment: nucleus (probable) Alternative splicing: named isoforms=2 Note: gene prediction based on EST data

General

C2H2 type zinc finger protein nuclear protein phosphoprotein

Properties

SIZE: entity length = 2723 aa MW = 305 kD COMPARTMENT: cell nucleus MOTIF: Zn finger C2H2-type SITE: 569-591 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 681-705 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 722-744 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 750-774 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 779-803 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 807-831 EFFECTOR-BOUND: Zn+2 MOTIF: Ser phosphorylation site {S820} Zn finger C2H2-type SITE: 1098-1123 EFFECTOR-BOUND: Zn+2 Ser phosphorylation site {S1159} Zn finger C2H2-type SITE: 1375-1397 EFFECTOR-BOUND: Zn+2 Ser phosphorylation site {S1628} coiled coil {1827-1854} Zn finger C2H2-type SITE: 1902-1927 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 1947-1972 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 2114-2139 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 2172-2197 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 2216-2241 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 2256-2281 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 2386-2410 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt O60281 Pfam PF00096 Entrez Gene 23036 Kegg hsa:23036