zinc finger protein 284 (ZNF284, ZNF284L)

Function: - role in transcriptional regulation Structure: - belongs to the krueppel C2H2-type zinc-finger protein family - contains 15 C2H2-type zinc fingers - contains 1 KRAB domain Compartment: nucleus Expression: - expressed in lung, liver, pancreas, thymus - lower expression in heart, placenta, spleen, prostate, ovary, small intestine, colon - no expression seen in brain, skeletal muscle, kidney, testis & peripheral blood leukocyte

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: MW = 69 kD entity length = 593 aa COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 8-78 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 145-169 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 175-197 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 203-225 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 231-253 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 259-281 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 287-309 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 315-337 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 343-365 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 371-393 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 399-421 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 427-449 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 455-477 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 483-505 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 511-533 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 539-561 EFFECTOR-BOUND: Zn+2

Database Correlations

UniProt Q2VY69 PFAM correlations Entrez Gene 342909

References

UniProt :accession Q2VY69