zinc finger protein 268; zinc finger protein HZF3 (ZNF268)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 24 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=2; ZNF268A; ZNF268B Expression: - highly expressed in 3-5 week-old embryos

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: entity length = 947 aa MW = 108 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 81-152 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 276-298 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 304-326 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 332-354 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 360-382 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 388-410 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 416-438 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 444-466 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 472-494 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 500-522 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 528-550 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 556-578 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 584-606 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 612-634 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 640-662 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 668-690 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 696-718 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 724-746 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 752-774 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 780-802 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 808-830 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 836-858 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 864-886 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 892-914 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 920-942 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 604753 UniProt Q14587 PFAM correlations Entrez Gene 10795 Kegg hsa:10795