zinc finger protein 267; zinc finger protein HZF2 (ZNF267)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 15 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable)

General

C2H2 type zinc finger protein nuclear protein phosphoprotein

Properties

SIZE: entity length = 743 aa MW = 87 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-75 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 267-289 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 322-340 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 380-402 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 408-430 EFFECTOR-BOUND: Zn+2 MOTIF: Thr phosphorylation site {T424} Zn finger C2H2-type SITE: 436-458 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 464-486 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 492-514 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 520-542 EFFECTOR-BOUND: Zn+2 MOTIF: Tyr phosphorylation site {Y520} Zn finger C2H2-type SITE: 548-570 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 576-598 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 604-626 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 632-654 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 660-682 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 688-710 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 716-738 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 604752 UniProt Q14586 Pfam PF01352 Entrez Gene 10308 Kegg hsa:10308