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zinc finger protein 254; bone marrow zinc finger 5; BMZF-5; hematopoietic cell-derived zinc finger protein 1; HD-ZNF1; zinc finger protein 539; zinc finger protein 91-like (ZNF254, BMZF5, ZNF539, ZNF91L)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn+2-finger protein family - contains 15 C2H2-type Zn+2 fingers - contains 1 KRAB domain Compartment: nucleus (probable) Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein nuclear protein phosphoprotein

Properties

SIZE: entity length = 659 aa MW = 77 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 13-84 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 210-232 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 238-260 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 266-288 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 294-316 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 322-344 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 350-372 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 378-400 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 406-428 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 434-456 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 462-484 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 490-512 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 518-540 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 546-568 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 574-596 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 602-624 EFFECTOR-BOUND: Zn+2 Thr phosphorylation site {T625}

Database Correlations

OMIM 604768 UniProt O75437 PFAM correlations Entrez Gene 9534 Kegg hsa:9534

References

  1. UniProt :accession O75437
  2. OMIM :accession 604768
  3. Entrez Gene :accession 9534