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zinc finger protein 217 (ZNF217, ZABC1)
Function:
- may be involved in transcriptional regulation
- may be a component of a BHC histone deacetylase complex
Structure:
- belongs to the krueppel C2H2-type Zn+2-finger protein family
- contains 7 C2H2-type Zn+2 fingers
Compartment: nucleus (probable)
General
C2H2 type zinc finger protein
phosphoprotein
transcription factor (TF)
Properties
SIZE: entity length = 1048 aa
MW = 115 kD
COMPARTMENT: cell nucleus
MOTIF: Zn finger C2H2-type
SITE: 65-88
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 128-150
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 156-178
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 216-238
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 375-397
EFFECTOR-BOUND: Zn+2
Ser phosphorylation site {S407}
Zn finger C2H2-type
SITE: 471-493
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 499-521
EFFECTOR-BOUND: Zn+2
Ser phosphorylation site {S570}
Ser phosphorylation site {S795}
Ser phosphorylation site {S848}
Database Correlations
OMIM 602967
UniProt O75362
Pfam PF00096
Entrez Gene 7764
Kegg hsa:7764
References
- UniProt :accession O75362
- Atlas of genetics & cytogenetics in oncology & haematology
http://atlasgeneticsoncology.org//genes/ZNF217ID42875ch20q13.html
Component-of
BHC histone deacetylase complex