zinc finger protein 181 (HHZ181, ZNF181)

Function: - transcriptional regulation (putative) Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 11 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (putative) Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: MW = 66 kD entity length = 571 aa COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-76 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 237-259 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 265-287 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 293-315 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 321-343 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 349-371 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 377-399 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 405-427 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 433-455 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 461-483 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 489-511 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 517-539 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 606741 UniProt Q2M3W8 PFAM correlations Entrez Gene 339318