zinc finger protein 18; zinc finger protein KOX11; heart development-specific gene 1 protein; zinc finger protein with KRAB & SCAN domains 6 (ZNF18, HDSG1, KOX11, ZKSCAN6)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 5 C2H2-type Zn⁺² fingers - contains 1 KRAB domain - contains 1 SCAN box domain Compartment: nucleus (putative) Alternative splicing: named isoforms=2

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 549 aa MW = 62 kD COMPARTMENT: cell nucleus MOTIF: scan box (LeR) {41-123} MOTIF: leucine residue (SEVERAL) Krueppel-associated box NAME: Krueppel-associated box SITE: 211-283 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 408-430 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 436-458 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 464-486 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 492-514 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 520-542 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194524 UniProt P17022 PFAM correlations Entrez Gene 7566 Kegg hsa:7566

References

UniProt :accession P17022