zinc finger protein 140 (ZNF140)

Function: transcriptional repressor (putative) Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 10 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (putative) Expression: - seems ubiquitous - expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney & pancreas

General

C2H2 type zinc finger protein transcriptional silencer (transcriptional repressor)

Properties

SIZE: entity length = 457 aa MW = 53 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 6-77 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 161-183 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 189-211 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 217-239 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 245-267 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 273-295 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 301-323 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 329-351 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 357-379 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 385-407 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 413-435 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 604082 UniProt P52738 PFAM correlations Entrez Gene 76999

References

UniProt :accession P52738