zinc finger protein 14; zinc finger protein KOX6; gonadotropin-inducible transcription repressor 4; GIOT-4 (ZNF14, GIOT4, KOX6)

Function: - may be involved in transcriptional regulation Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 19 C2H2-type Zn⁺² fingers - contains 1 KRAB domain Compartment: nucleus (probable)

General

C2H2 type zinc finger protein transcription factor (TF)

Properties

SIZE: entity length = 642 aa MW = 75 kD COMPARTMENT: cell nucleus MOTIF: Krueppel-associated box NAME: Krueppel-associated box SITE: 4-76 MOTIF: KRAB A box KRAB B box EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 103-125 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 141-163 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 169-191 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 197-217 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 223-245 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 251-273 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 279-301 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 307-329 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 335-357 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 363-385 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 391-413 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 419-441 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 447-469 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 475-497 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 503-525 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 531-553 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 559-581 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 587-609 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 615-637 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 194556 UniProt P17017 PFAM correlations Entrez Gene 7561 Kegg hsa:7561

References

UniProt :accession P17017