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zinc finger protein 131 (ZNF131)
Function:
- may be involved in transcriptional regulation
- plays a role during development & organogenesis & in the adult central nervous system (putative)
Structure:
- belongs to the krueppel C2H2-type Zn+2-finger protein family
- contains 1 BTB (POZ) domain
- contains 6 C2H2-type Zn+2 fingers
Compartment: nucleus (putative)
Alternative splicing: named isoforms=2
Expression:
- predominant expression in different brain areas including occipital lobe, temporal lobe, caudate nucleus, hippocampus, cerebellum
- expressed in testis & thymus
General
C2H2 type zinc finger protein
transcription factor (TF)
Properties
SIZE: entity length = 623 aa
MW = 71 kD
COMPARTMENT: cell nucleus
MOTIF: BTB domain {34-98}
MOTIF: Zinc finger
NAME: Zinc finger
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 261-283
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 288-311
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 328-350
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 356-381
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 392-414
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 420-443
EFFECTOR-BOUND: Zn+2
Database Correlations
OMIM 604073
UniProt P52739
PFAM correlations
Entrez Gene 7690
References
UniProt :accession P52739