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zinc finger BED domain-containing protein 6 (ZBED6)
Function:
- transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3' & represses transcription of IGF2
- may also regulate expression of other target genes containing this consensus binding site (putative)
Structure:
- contains 2 BED-type Zn+2 fingers
Compartment:
- nucleus, nucleolus (putative)
- located predominantly in the nucleolus butalso dispersed throughout the nucleus (putative)
Notes:
- encoded by an exapted DNA transposon located in an intron of the ZC3H11A gene
General
nuclear protein
zinc finger protein
Properties
SIZE: entity length = 979 aa
MW = 110 kD
COMPARTMENT: cell nucleus
MOTIF: Zinc finger
NAME: Zinc finger
SITE: 130-187
EFFECTOR-BOUND: Zn+2
Zinc finger
NAME: Zinc finger
SITE: 264-321
EFFECTOR-BOUND: Zn+2
Database Correlations
UniProt P86452
PFAM correlations
References
UniProt :accession P86452