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zinc finger & BTB domain-containing protein 10; zinc finger protein RIN ZF (ZBTB10, RINZF, RINZFC)
Function:
- may be involved in transcriptional regulation
- phosphorylated upon DNA damage, probably by ATM or ATR
Structure:
- contains 1 BTB/POZ domain
- contains 2 C2H2-type Zn+2 fingers
Compartment: nucleus (putative)
Alternative splicing: named isoforms=2
General
phosphoprotein
Zinc finger & BTB domain containing protein
Properties
SIZE: entity length = 847 aa
MW = 92 kD
COMPARTMENT: cell nucleus
MOTIF: proline-rich region
SITE: 39-58
MOTIF: proline residue (SEVERAL)
glycine-rich region {101-228}
MOTIF: Ser phosphorylation site {S210}
BTB domain {364-433}
MOTIF: Zinc finger
NAME: Zinc finger
EFFECTOR-BOUND: Zn+2
Ser phosphorylation site {S565}
Ser phosphorylation site {S647}
Zn finger C2H2-type
SITE: 698-720
EFFECTOR-BOUND: Zn+2
Thr phosphorylation site {T721}
Zn finger C2H2-type
SITE: 726-748
EFFECTOR-BOUND: Zn+2
Database Correlations
UniProt Q96DT7
Pfam PF00651
Entrez Gene 65986
Kegg hsa:65986
References
UniProt :accession Q96DT7